Scientist - Biologics Job at Bristol-Myers Squibb, Princeton, NJ

  • Bristol-Myers Squibb
  • Princeton, NJ

Job Description

Working with Us Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: . This position will be part of the Pharmaceutical Candidate Optimization (PCO) within the Discovery Research organization located in Lawrenceville, NJ. The PCO organization is an integrated function with responsibility for characterizing nonclinical safety, DMPK and early CMC properties of lead candidates to identify and solve issues, guiding project teams in the discovery of high quality drug candidates and enable their clinical development and successful marketing authorizations across the globe. We are seeking a collaborative, self-motivated and results oriented scientist with a passion for problem solving to extend and enhance patient's lives, with a focus on understanding lead candidate developability and liabilities. The successful candidate excels in a fast-paced, collaborative, cross functional, matrix team environment to enable the candidate nomination and progression for biologics, and emerging modalities such as, but not limited to, antibody-drug conjugates, gene therapies, oligonucleotides, etc. The scientist will conduct studies to define and understand biophysical, chemical and preformulation properties using a wide variety of analytical characterization tools to work directly with teams to guide the discovery and identification of next generation therapies. When you join BMS, you are joining a diverse, high-achieving team united by a common mission. Here, you'll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You'll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma. Job Responsibilities

  • Ability to carry out biophysical characterization and preformulation studies on potential new biologic candidates, with the purpose to define their developability and liability profiles.
  • Provide experimental and computational input to protein discovery scientists during design and screening of new biologics entities and enable drug design from lead optimization to the point of candidate identification, characterization and selection.
  • Assist in the design and development of formulations suitable for use in drug discovery pharmacology studies, PK studies and initial exploratory toxicology studies.
  • Participate in driving the strategic direction of the Discovery Pharmaceutics & Analytical Sciences group to further its ability to act as a problem solving entity for biologics discovery teams and provide seamless transfer of candidates to development.
  • Help advance the abilities of the larger preclinical optimization organization to develop expertise in scientific areas which can enhance our understanding of the role of biophysical properties in the overall biopharmacetuical performance of proteins, antibodies and other large molecules.
Basic Qualifications: Bachelor's with 5+ years of Academic or Industry experience OR Master's Degree with 3+ years of Academia or Industry experience OR PhD Preferred Qualifications: Ph.D. with 0-2 years of experience or MS with 3+ years of experience with degree in Pharmaceutics, Biochemistry, Chemistry, Pharmaceutical Chemistry, Molecular Biology, Bioengineering, Chemical Engineering or related disciplines Knowledge of basic protein chemistry and biopharmaceutical principles as they apply to drug discovery and drug delivery of proteins, antibodies and other large molecules. Understanding of biophysical properties and analytical methods used for characterization of proteins and other large molecules and how they relate to the biologics' in vivo delivery and disposition. Strong understanding of preformulation aspects for proteins, antibodies and other large molecules is necessary along with ability to guide the generation and interpretation of preformulation data as it relates to the overall discovery process. Good written and verbal communication skills are a must. Excellent interpersonal skills demonstrating effectiveness as a team player on multidisciplinary teams resourced in a flexible and global environment is required. The ability to think innovatively and reduce such thinking to practical implementation is desired. Knowledge on use of computers and databases for data collection, compilation, analysis and information dissemination is a must. If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career. Uniquely Interesting Work, Life-changing Careers With a single vision as inspiring as Transforming patients' lives through scienceā„¢ , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues. On-site Protocol BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role: Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function. BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to . Visit eeo -accessibility to access our complete Equal Employment Opportunity statement. BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters. BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Job Tags

Remote job, Flexible hours, Shift work,

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